Sister Sex Lesbian, a female person who. n. Although the term typically refers to a familial relationship, it is sometimes used endearingly to refer to non-familial relationships. How to use sister in a sentence. Apr 22, 2026 ยท sister (plural sisters or (archaic in most senses) sistren) A daughter of the same parents as another person; a female sibling. SISTER definition: 1. → See half-sister, stepsister 3. [1] The male counterpart is a brother. Tia Landry and Tamera Campbell are twins separated at birth who learn of each other's existence as teenagers and reunite. 1.
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